I read with considerable interest the editorial “ ‘No Excuses’ for the Future of Green Chemistry” (C&EN, June 2/9, 2025, page 2) and the first installment of the new column on green chemistry, “The ...

Organic green chemistry merges fundamental synthetic and analytical advances to develop chemical transformations that meet sustainability criteria. It emphasises minimising waste at source rather than ...

The adoption of water as a primary reaction medium has revolutionised sustainable organic synthesis by eliminating or drastically reducing the need for traditional organic solvents. Both “in-water” ...

Highly reactive organometallic reagents, like organolithiums (molecules with a carbon–lithium bond) are essential reagents in organic synthesis because of their applications from polymer synthesis to ...

Organic chemist Bruce Lipshutz had a bit of a rude awakening. It was around 2007, and the head of environmental health and safety (EH&S) at the University of California, Santa Barbara, sat Lipshutz ...

Peptides, as essential biomolecules linking amino acids and proteins, play a vital role across numerous disciplines, including life science research, drug discovery, biomaterials engineering, and ...

Penn State researchers have uncovered a surprising twist in a foundational chemical reaction known as oxidative addition. Typically believed to involve transition metals donating electrons to organic ...

Figure 1. LoRA-Chem: From Model Customization to Organic Chemistry Reaction Tasks. (a) Several machine learning algorithm paradigms applied to organic chemistry. (b) Inspired by AI-driven image style ...